For the past half-century, structural biologists relied on the notion that similar protein sequences give rise to similar structures and functions. While this assumption has driven research to explore ...
The AF fibrillarin–Nop5p complex structure is dumbbell-shaped, with maximum dimensions of 138 × 75 × 54 Å (Fig. 1b,c). Each Nop5p is bound with one fibrillarin molecule, and two such fibrillarin–Nop5p ...