NHS to make Jewish BRCA genetic testing program permanent after successful pilot

Those with Ashkenazi Jewish ancestry have a one in 40 chance of carrying a BRCA1 or BRCA2 compared to a one in 250 chance for ...
Healthline

What to Know About Transthyretin Amyloidosis (ATTR) Genetic Testing

Genetic testing for ATTR can detect transthyretin mutations and offer crucial information about risk, monitoring, and treatment, if needed. Transthyretin amyloidosis (ATTR) is a genetic condition that ...
Fred Hutch

Testing for hereditary cancers can be a lifesaver

For Josh Henderson, 66, of Olympia, getting genetic testing was a no-brainer. “The first time I came to Fred Hutch, my oncologist suggested it,” said the retired IT manager who received a metastatic ...

New tool helps uncover rare genetic mutations in common diseases, including Parkinson's

Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that ...
Nature

A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects

Mutation rates and biases in mutational sequence context can be influenced by endogenous cellular processes, environmental exposures, and genetic variation. All such mutagenic processes can leave ...
Medical Xpress

Genetic mutation predicts pancreatic cancer metastasis and survival

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation—KRAS circulating tumor DNA (ctDNA)—strongly indicates a higher risk of cancer ...

With Genetic Testing, How Much Information Is Too Much?

A National Institutes of Health study will evaluate whether to screen tens of thousands of healthy infants for genetic ...

Astrologer Maren Altman Says She's Exploring End-of-Life Care Options After Testing Positive for Fatal Genetic Mutation

The 27-year-old astrologer and content creator took to Instagram to share her C9ORF72 genetic mutation diagnosis ...
Nature

Increasing genetic testing for breast cancer genes

Integrating new AI screening tools for BRCA and HRD breast-cancer mutations into routine care could lead to earlier detection, more precise treatment, and lives saved. If they are aware of the threat, ...
The Forward

How one Jewish geneticist turned a family tragedy into a lifesaving mission.

Editor’s note: This essay was adapted from “The Dressmaker’s Mirror,” a new book about sudden death and Ashkenazi Jewish mutations. In Jewish communities, conversations about genetic risks often focus ...
Medscape

FDA Approves Genetic Test for KRAS Mutation in CRC Patients

July 6, 2012 — The US Food and Drug Administration (FDA) has approved the therascreen® KRAS RGQ PCR Kit to be sold as a companion diagnostic test for cetuximab (Erbitux). In addition, the FDA has ...
New York Post

‘Alcohol gene’ could predict how cocktails may affect you — and there’s a test for it

Do you experience nausea, facial flushing or a racing heart after enjoying even small amounts of your favorite cocktail? These could be signs that you have an inherited intolerance to alcohol — and a ...