University of Chicago researchers have developed a liquid biopsy test based on modification patterns in microbiome-derived cell-free RNA that predicts colorectal cancer (CRC) with greater accuracy ...

Schematic depiction of the principal components of epitranscriptomic mechanisms and their involvement in malignant hematopoiesis. Writers and erasers of main reversible methylations are represented in ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

RNA epigenetics also called Epitranscriptomics is an evolving field of research that explores chemical modifications on RNA and their impact on the cell and ...

Deciphering the spatial, temporal and chemical complexity of RNA molecules in living systems is key to understanding gene regulation at the molecular level. Recent advances in imaging, molecular ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

RNA modifications have emerged as a pivotal area of focus in molecular biology and precision medicine. Recent breakthroughs highlight the dynamic nature of ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self ...